• Middle East J Anaesthesiol · Oct 1999

    Comparative Study Clinical Trial Controlled Clinical Trial

    Comparison between two different propofol dosage regimens for insertion of cuffed oro-pharyngeal airway.

    • G S Voyagis, V Dimitriou, G Kostantopoulou, and N Charissi.
    • Department of Anesthesiology, Sotiria Hospital, Athens, Greece.
    • Middle East J Anaesthesiol. 1999 Oct 1; 15 (3): 273-9.

    AbstractConditions for insertion of the cuffed oropharyngeal airway (COPA) were assessed following two different dosage regimens of propofol: group I (n = 40): 1.5 mg.kg-1; group II (n = 40): 2.5 mg.kg-1. The insertion conditions were evaluated by using a scoring system (-, + and +2) of gag and cough reflexes. The necessary use of additional dosage of propofol and the duration of post-induction apnea were also recorded. There were no significant differences between the two groups in the incidence of coughing, gagging and the additional usage of induction agent. The mean (+/- SD) duration of apnea was significantly longer in the high dose group: 9 +/- 6 min vs 5 +/- 7 min (p = 0.007). Low dose of propofol combines efficient insertion conditions with decreased length of post-induction apnea.

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