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- Bo Angela Wan, William Pidduck, Liying Zhang, Amy Nolen, Caitlin Yee, Katie Wang, Selina Chow, Stephanie Chan, Leah Drost, Hany Soliman, Eric Leung, Philomena Sousa, Donna Lewis, Carlo DeAngelis, Prince Taylor, and Edward Chow.
- Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
- Pain Manag Nurs. 2021 Jun 1; 22 (3): 402-407.
BackgroundPatients who receive radiation treatment (RT) for breast cancer often report pain, which contributes negatively to quality of life (QoL).AimsTo identify demographic, treatment, and disease characteristics associated with pain and changes in pain before and after RT using the Edmonton Symptom Assessment Scale (ESAS).DesignRetrospective study.SettingsOdette Cancer Centre.ParticipantsPatients diagnosed with nonmetastatic breast cancer from January 2011-June 2017 with at least one ESAS completed pre-RT and one completed post-RT.MethodsData on systemic treatment, radiation, patient demographics, and disease stage were extracted. To identify factors associated with pain before and after RT and changes in pain, univariate and multivariate general linear regression analysis were conducted. p < .05 was considered statistically significant.ResultsThis study included 1,222 female patients with a mean age of 59 years. ESAS was completed an average of 28 days before RT (baseline) and 142 days after RT, respectively. In multivariable analysis, higher baseline pain scores were associated with having recently completed adjuvant chemotherapy (p = .002) and eventual receipt of locoregional (p = .026) or chest wall (p = .003) radiation. Adjuvant chemotherapy (p = .002) and chest wall radiation (p = .03), were associated with a significant reduction in pain score after radiotherapy, while locoregional RT was associated with a higher pain score after RT (p < .001).ConclusionsPatients with locoregional RT had higher baseline pain that remained elevated after RT completion and should be screened for pain and provided with pain management and support when necessary.Copyright © 2021. Published by Elsevier Inc.
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