• Revista médica de Chile · Jun 2020

    [The present situation of colorectal cancer in Chile].

    • Juvenal A Ríos, M Francisca Barake, María José Arce, Francisco López-Köstner, Tomas P Labbe, Jessica Villena, and Sergio Becerra.
    • Escuela de Medicina, Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile.
    • Rev Med Chil. 2020 Jun 1; 148 (6): 858-867.

    AbstractColorectal (CRC) is one of the most common types of cancer worldwide. Most tumors develop from an adenoma in a period of 10 to 15 years, but some may appear without previous adenomatous lesions. Seventy-five percent of colorectal cancers are sporadic, 20% have a family component (first or second-degree relatives with CRC) and 5% have a hereditary predisposition with a Mendelian pattern. The epidemiological evolution in the recent years in Chile has a worrisome evolution and the treatment costs of advanced stages are a burden for the healthcare system. We herein highlight the main Chilean medical and scientific contributions on the pathogenesis, early diagnosis, and treatment of CRC, which lead to its better understanding, and therefore better management, based on local evidence.

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