• Can J Anaesth · Apr 1992

    Anaesthesia for Charcot-Marie-Tooth disease: a review of 86 cases.

    • J F Antognini.
    • Department of Anesthesiology, University of California, Davis Medical Center, Sacramento 95817.
    • Can J Anaesth. 1992 Apr 1; 39 (4): 398-400.

    AbstractOperative charts were reviewed in 86 patients with Charcot-Marie-Tooth disease, a condition characterized by chronic muscular denervation. A total of 161 surgical procedures was performed. Major complications were few, and only one operative death occurred, unrelated to anaesthesia. Succinylcholine and malignant hyperthermia triggering agents were used in 41 (48%) and 77 (90%) patients, respectively, without untoward effects. Contrary to previous reports, this survey supports the safe use of succinylcholine and MH triggering agents in this disease.

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