• Virol J · Jul 2020

    Review

    SARS-CoV-2: characteristics and current advances in research.

    • Yicheng Yang, Zhiqiang Xiao, Kaiyan Ye, Xiaoen He, Bo Sun, Zhiran Qin, Jianghai Yu, Jinxiu Yao, Qinghua Wu, Zhang Bao, and Wei Zhao.
    • State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
    • Virol J. 2020 Jul 29; 17 (1): 117.

    AbstractCoronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has spread rapidly across the world and become an international public health emergency. Both SARS-CoV-2 and SARS-CoV belong to subfamily Coronavirinae in the family Coronaviridae of the order Nidovirales and they are classified as the SARS-like species while belong to different cluster. Besides, viral structure, epidemiology characteristics and pathological characteristics are also different. We present a comprehensive survey of the latest coronavirus-SARS-CoV-2-from investigating its origin and evolution alongside SARS-CoV. Meanwhile, pathogenesis, cardiovascular disease in COVID-19 patients, myocardial injury and venous thromboembolism induced by SARS-CoV-2 as well as the treatment methods are summarized in this review.

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