• Dtsch. Med. Wochenschr. · Feb 2021

    Review

    [Axial spondyloarthritis - Update 2021].

    • Denis Poddubnyy.
    • Charité-Universitätsmedizin Berlin, Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Berlin, und Deutsches Rheumaforschungszentrum, Epidemiologie, Berlin.
    • Dtsch. Med. Wochenschr. 2021 Feb 1; 146 (3): 185-190.

    AbstractNew data for the diagnosis of axial spondyloarthritis on the specificity of active inflammatory changes in sacroiliac joints were generated recently and are reviewed here. A new magnetic resonance imaging sequence to improve the detection of erosions is discussed. Tumor necrosis factor (TNF) and Interleukin-17 (IL-17) inhibitors are now approved as therapy for both radiographic and non-radiographic forms of axial spondyloarthritis. Janus kinase inhibitors delivered promising results in Phase II/III studies. For the inhibition of structural progression new data are discussed on slowing structural progression in the spine under TNF and IL-17 inhibitors.Thieme. All rights reserved.

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