• Mark Krakauer, Mark Armando Prendes, Byron Wilkes, Hui Bae Harold Lee, Mostafa Fraig, and William R Nunery.
• *Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana; †Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky; ‡Department of Ophthalmology, University of Washington, Seattle, Washington; and §Department of Ophthalmology, University of Tennessee, Memphis, Tennessee, U.S.A.
• Ophthal Plast Reconstr Surg. 2016 May 1; 32 (3): e71-2.

AbstractHistoplasma capsulatum var capsulatum is a dimorphic fungus endemic to the Ohio and Mississippi River Valleys of the United States. In this case report, a 33-year-old woman who presented with a right orbital mass causing progressive vision loss, diplopia, and facial swelling is described. Lateral orbitotomy with lateral orbital wall bone flap was performed for excisional biopsy of the lesion. The 1.5 × 1.8 × 2.3 cm cicatricial mass demonstrated a granulomatous lesion with necrosis and positive staining consistent with Histoplasma capsulatum var capsulatum infection. To the authors' knowledge, this is the first case of orbital histoplasmosis to be reported in the United States and the first case worldwide of orbital histoplasmosis due to Histoplasma capsulatum var capsulatum.

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