• Head & neck · Dec 2011

    Case Reports

    Laryngeal cancer involving a branchial cleft cyst.

    • Jonathan B Ida, Matthew W Stark, Zhenggong Xiang, and Mary M Fazekas-May.
    • Department of Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio, USA. jonathan.ida@cchmc.org
    • Head Neck. 2011 Dec 1; 33 (12): 1796-9.

    BackgroundBenign secondary neck lesions in the setting of laryngeal cancer have been described, but not with branchial cleft cysts. This article describes a branchial cleft cyst in a laryngectomy/neck dissection specimen.Methods And ResultsA 44-year-old woman presented to our emergency department with an obstructing laryngeal tumor that was staged as a T4N0M0 squamous cell cancer on the basis of clinical and radiographic findings. After laryngectomy with bilateral neck dissections, the neck specimen contained a right-sided branchial cleft cyst, which was directly invaded by tumor. In addition, the location of the cyst relative to the larynx suggested that this was a third branchial cleft cyst.ConclusionThis is the first report of a laryngeal carcinoma invading a branchial cleft cyst. Staging discrepancies may result from concurrent head and neck lesions, altering treatment plans, or changing the prognosis for the patient. Lesions such as this are nearly impossible to diagnose preoperatively, and a high index of suspicion for advanced cancer should be maintained.Copyright © 2010 Wiley Periodicals, Inc.

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