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- Z Tazi Mezalek.
- Service médecine interne - hématologie clinique, hôpital Ibn Sina, Rabat, Maroc; Faculté de médecine et de pharmacie, université Mohammed VI, Rabat, Maroc. Electronic address: z.tazimezalek@gmail.com.
- Rev Med Interne. 2021 Feb 1; 42 (2): 93-100.
AbstractThe SARS-CoV-2 virus caused a global pandemic within weeks. Many patients with severe COVID-19 present with coagulation abnormalities, including increase D-dimers. This coagulopathy is associated with an increased risk of death. Furthermore, a substantial proportion of patients with severe COVID-19 develop sometimes unrecognized, venous thromboembolic complications. A better understanding of COVID-19 pathophysiology, in particular hemostatic disorders, will help to choose appropriate treatment strategies. A rigorous thrombotic risk assessment and the implementation of a suitable anticoagulation strategy are required. We review here the characteristics of COVID-19 coagulation laboratory findings in affected patients, the incidence of thromboembolic events and their specificities, and potential therapeutic interventions.Copyright © 2021 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.
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