• Arq Neuropsiquiatr · Jan 2014

    Randomized Controlled Trial

    Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program.

    • Leonardo Halley Carvalho Pimentel, Francisco José Alencar, Leonardo Raphael Santos Rodrigues, Sousa Francisca Cléa Florenço de FC Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, FortalezaCE, Brazil., and João Batista Mendes Teles.
    • Centro Integrado de Reabilitação, TeresinaPI, Brazil.
    • Arq Neuropsiquiatr. 2014 Jan 1; 72 (1): 28-32.

    UnlabelledThe objective of this study was to evaluate the effects of botulinum toxin type A (BTX-A) on spastic foot in stroke patients in a rehabilitation program.MethodHemiparetic stroke patients (n=21) enrolled in a rehabilitation program were divided into two groups. The first group (n=11) received a total of 300 UI BTX-A, and the second group (n=10) received 100 UI BTX-A. All patients were assessed at baseline and 2, 4, 8 and 12 weeks after injection for Modified Ashworth Score, time walking 10 meters, and the Functional Independence Measure (mFIM) motor score.ResultsThe higher-dose group exhibited a significant improvement in spasticity, and both groups showed an improvement in time walking 10 meters and mFIM, with no significant differences between them.ConclusionsOur findings suggest that gains in gait velocity and functional independence were not correlated to BTX-A dose.

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