• Medicina clinica · Apr 2021

    Review

    Multi-drug resistant tuberculosis, ten years later.

    • José Antonio Caminero Luna, Guillermo Pérez Mendoza, and Felipe Rodríguez de Castro.
    • Unidad de Tuberculosis y Micobacteriosis, Servicio de Neumología, Hospital General de Gran Canaria «Dr. Negrin», Las Palmas de Gran CanariaEspaña. Electronic address: jcamlun69@gmail.com.
    • Med Clin (Barc). 2021 Apr 23; 156 (8): 393-401.

    AbstractDrug-resistant tuberculosis, especially those with resistance to rifampicin (RR-TB), has become one of the main obstacles to achieving the dream of eradicating tuberculosis. Furthermore, it is necessary to combine three or four different drugs in the attempt to cure TB, however, unfortunately, there are few available that can be considered genuinely effective. Fortunately, the notable worldwide increase in RR-TB in recent years has led to the investment of resources in the development of new drugs for TB, and other drugs investigated for other diseases have been successfully tested on TB. This has resulted in a clear change in the clinical management of these patients over the last 3-4 years, and it is now easier to design therapeutic regimens and achieve higher success rates. All these changes are updated in this review.Copyright © 2020 Elsevier España, S.L.U. All rights reserved.

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