• Eur Spine J · May 2015

    Case Reports

    Effective treatment of delayed union of a lumbar vertebral fracture with daily administration of teriparatide in a patient with diffuse idiopathic skeletal hyperostosis.

    • Takuji Matsumoto, Muneharu Ando, and Shunji Sasaki.
    • Department of Orthopedic Surgery, Nokami Kosei General Hospital, 198 Kobata, Kimino-Cho, Kaisou-Gun, Wakayama, 640-1141, Japan, matsumoto_t@nokami-hospital.jp.
    • Eur Spine J. 2015 May 1;24 Suppl 4:S573-6.

    IntroductionWe herein describe a case of delayed union of a lumbar spine fracture in a 70-year-old patient with diffuse idiopathic skeletal hyperostosis (DISH).Clinical Course And ResultBecause he decided not to undergo surgical treatment, we provided conservative treatment with teriparatide (TPTD). Union was obtained in 2 months, and no adverse events were observed during treatment. Six months after starting the TPTD, further bone formation was observed and the lumbar instability had resolved.ConclusionThis is the first report of successful use of TPTD to treat delayed union of a spine fracture in a patient with DISH without surgical intervention.

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