• Neurologic clinics · Feb 2012

    Review

    Ischemic stroke: emergencies and management.

    • Roger E Kelley and Sheryl Martin-Schild.
    • Department of Neurology, Tulane University School of Medicine, 1430 Tulane Avenue 8065, New Orleans, LA 70112, USA. rkelley2@tulane.edu
    • Neurol Clin. 2012 Feb 1; 30 (1): 187-210, ix.

    AbstractThe past 40 years have seen the evolution of acute ischemic stroke management from unproven therapies du jour, such as steroids, heparin for stroke in evolution, and hypervolemic-hemodilution, to more of a scientific basis for our decision-making process. This evolution is directly related to the advancements in imaging of stroke. It is also related to carefully designed, controlled clinical trials of potential therapies, which have led to the recognition of the benefits of thrombolytic therapy in the acute setting but have also caused confusion and frustration over the lack of benefit for potential neuroprotective agents that once seemed promising.Copyright © 2012 Elsevier Inc. All rights reserved.

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