• Jili Zhang, Jialing Wu, and Xiukun Hou.
• Dalian Medical University.
• Medicine (Baltimore). 2021 Jan 29; 100 (4): e23635e23635.

BackgroundAs a novel ultrasound technique, superb microvascular imaging (SMI) can quickly, simply, and noninvasively study the microvascular distribution in the tumor and evaluate the microvascular perfusion. Studies suggested that SMI is helpful for the differentiation between benign and malignant parotid tumors. However, the results of these studies have been contradictory. Therefore, the present meta-analysis aimed at determining the accuracy of SMI in the differential diagnosis between benign and malignant parotid tumors.MethodsWe will search PubMed, Web of Science, Cochrane Library, and Chinese biomedical databases from their inceptions to September 30, 2020, without language restrictions. Two authors will independently carry out searching literature records, scanning titles and abstracts, full texts, collecting data, and assessing risk of bias. Review Manager 5.2 and Stata14.0 software will be used for data analysis.ResultsThis systematic review will determine the accuracy of SMI in the differential diagnosis between benign and malignant parotid tumors.ConclusionIts findings will provide helpful evidence for the accuracy of SMI in the differential diagnosis between benign and malignant parotid tumors.Systematic Review RegistrationINPLASY2020100093.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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