• Medicine · Jan 2021

    Efficacy and safety of ligation of intersphincteric fistula tract in the treatment of anal fistula: A protocol for systematic review and meta-analysis.

    • Jiaji Zhang, Xilu Hao, Yican Zhu, and Ronggang Luan.
    • Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu province, China.
    • Medicine (Baltimore). 2021 Jan 29; 100 (4): e23700e23700.

    BackgroundAnal fistula is characterized with perianal cellulitis, anorectal pain, smelly or bloody drainage of pus, and difficulty in controlling bowel movements. Ligation of intersphincteric fistula tract (LIFT) technique is a recently developed approach against anal fistula, and it could alleviate the pain of the patient, with little postoperative trauma, which can greatly shorten the wound healing time and hospitalization stay. We conduct the meta-analysis and systematic review to systematically evaluate the clinical efficacy and safety of LIFT in the treatment of anal fistula.MethodsRandomized controlled trials of LIFT against anal fistula will be searched in several Chinese and English databases. Two reviewers will independently conduct the literature extraction and risk of bias assessment. Statistical analysis will be conducted in RevMan 5.3.Results And ConclusionsThe study will help to systematically evaluate the clinical efficacy and safety of LIFT in the treatment of anal fistula.Osf Registration NumberDOI 10.17605/OSF.IO/T4FUH.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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