• Yanfei Du, Yuyan Jiang, Shujuan Tang, and Lijie Li.
• Department of Ultrasound, Liaocheng People's Hospital.
• Medicine (Baltimore). 2021 Jan 29; 100 (4): e23905e23905.

BackgroundPapillary thyroid microcarcinoma is easy to be missed because of its small focus, concealed incidence and lack of clinical features. Ultrasound examination is one of the main methods for the detection and diagnosis of papillary thyroid microcarcinoma. The detection rate of conventional ultrasound is not ideal. Combined ultrasound elastography can improve the detection rate, but there is lack of evidence-based evidence. The purpose of this study was to systematically evaluate the value of conventional ultrasound combined with ultrasound elastography in the diagnosis of papillary thyroid microcarcinoma.MethodsA systematic search was performed by retrieving on English databases (PubMed, Embase, Web of Science, the Cochrane Library) and Chinese databases (CNKI, Wanfang, Weipu (VIP), CBM). The retrieval time limit was from the establishment of the database to November 2020 and manually search for the conventional ultrasound combined with ultrasound elastography in the diagnosis of papillary thyroid microcarcinoma. Two researchers extracted and evaluated the quality of the data in the included study independently. A meta-analysis was performed using Meta Disc1.4 and RevMan5.3 software.ConclusionsThis study will evaluate the accuracy and practicability of conventional ultrasound combined with ultrasonic elastography in the diagnosis of papillary thyroid microcarcinoma, and provide evidence-based basis for clinicians to choose the appropriate or best diagnostic method.Ethics And DisseminationThe private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required.Osf Registration NumberDOI: 10.17605 / OSF.IO / V6HK7.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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