• Eur Spine J · May 2015

    Case Reports

    Intractable hiccups caused by syringobulbia and syringomyelia associated with intramedullary spinal hemangioblastoma.

    • Je Hoon Jeong, Soo-Bin Im, Dong-Seong Shin, Sun-Chul Hwang, and Bum-Tae Kim.
    • Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, 1174 Jung-1-dong, Wonmi-gu, Bucheon, Gyunggi, 424-767, Republic of Korea.
    • Eur Spine J. 2015 May 1;24 Suppl 4:S614-8.

    IntroductionHiccups caused by a neoplasm in the spinal cord are rare.Materials And MethodsWe report a case of intractable hiccups caused by syringobulbia and syringomyelia associated with cervical intramedullary spinal hemangioblastoma, which was successfully treated by surgical excision. A 60-year-old man was referred from the neurology department after presenting with hiccups for 1 year. The hiccups were aggravated 3 months ago and were sustained during eating or sleeping. Several doctors administered a muscle relaxant and an anticonvulsant, but they were ineffective. Spinal MRI revealed a huge syringomyelia from C2 to T2, associated with a highly enhancing intramedullary mass lesion at the C5 level. The hiccups were ceased after removal of the tumor through a right hemilaminectomy. The pathology of the specimen was hemangioblastoma. The size of the syringobulbia and syringomyelia decreased markedly on MRI checked 5 months after surgery.ConclusionsIntractable hiccups can be caused by syringobulbia associated with an intramedullary cord tumor in the cervical area and possible mechanisms of hiccups were reviewed.

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