• Xiaorong Cheng, Shunqin Mao, Yibao Zhang, Xiaoyun Peng, Rui Ma, Yingcun Bao, Qun Li, Mei Liu, Dengjuan Sun, Bo Wan, Lulu Wang, and Fang Zhang.
• Department of Rehabilitation Medicine, Second Hospital of Lanzhou University, Lanzhou, China.
• Medicine (Baltimore). 2021 Jan 22; 100 (3): e24219e24219.

BackgroundThe intracerebral hemorrhagic stroke (ICH) is associated with high mortality and severe disability in survivors, which causing about 42% of the disability-adjusted life years lost and 50% of all stroke patients dead within 1 year. Although early functional training is recommended to facility rehabilitation after the stroke, the benefit and safety are still controversial.IntroductionThis systematic review aims to investigate whether early physical rehabilitation could have a beneficial effect for the patients with ICH compared with standard rehabilitation care.Methods And AnalysisPubmed, Embase, and Cochrane library will be searched to include randomized control trials which investigate the rehabilitation effective of the early mobilization for patients with ICH compared with routine nursing or standard care. Rev-Man version 5.3 will be used to perform all calculations related to the meta-analysis. Dichotomous data will be calculated in terms of a fixed or random effect model and expressed by the relative risk (RR) with 95% confidence interval (CI). The Cochrane collaborations tool in the following aspects was used to assess the risk of bias (ROB) in included studies. The inconsistency index (I2) and Chi-Squared will be applied for heterogeneity detection between clinical trials. A value of P < .05 will be considered statistically significant.ConclusionThis study will explore the role of early physical rehabilitation and provide insight for clinicals to improve rehabilitation results of ICH.Registration NumberINPLASY2020110068.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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