• Medicine · Jan 2021

    Negative pressure wound therapy for skin necrosis prevention after snakebite in the emergency department: A retrospective cohort study.

    • Kwan Jae Kim, Jin Hong Min, Insool Yoo, Seung Whan Kim, Jinwoong Lee, Seung Ryu, Yeon Ho You, Jung Soo Park, Won Joon Jeong, Yong Chul Cho, Se Kwang Oh, Yong Nam In, Hong Joon Ahn, Chang Shin Kang, Hyunwoo Kyung, Byung Kook Lee, Dong Hun Lee, and Dong Hoon Lee.
    • Department of Emergency Medicine, Chungnam National University Hospital, 282.
    • Medicine (Baltimore). 2021 Jan 22; 100 (3): e24290.

    AbstractThis retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites.Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results.Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001).These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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