• Dermatologic therapy · Jul 2019

    Review Case Reports

    Rapid remission of Stevens-Johnson syndrome by combination therapy using etanercept and intravenous immunoglobulin and a review of the literature.

    • Ruojun Wang, Shaomin Zhong, Ping Tu, Ruoyu Li, and Mingyue Wang.
    • Department of Dermatology, Peking University First Hospital, Beijing, China.
    • Dermatol Ther. 2019 Jul 1; 32 (4): e12832.

    AbstractStevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are spectrum of rare, acute, and life-threatening delayed-type drug hypersensitivity reactions that are associated with high mortality rates. However, no therapeutic standard has been proposed for SJS/TEN. Here, we report a case of a patient diagnosed with Stevens-Johnson syndrome whose disease progression was halted by a single dose of etanercept and was treated successfully. In addition, we reviewed the literature reporting patients with SJS/TEN treated with similar regimens.© 2019 Wiley Periodicals, Inc.

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