• Natl Med J India · Jan 2020

    Case Reports

    Invasive fungal infection with a rare organism in a patient with acute myeloid leukaemia.

    • Mehmet Baysal, Elif Ümit, Ali Caner Ozdover, Onur Kirkizlar, and Ahmet Muzaffer Demir.
    • Department of Haematology, Trakya University Faculty of Medicine, Balkan Yerleskesi 22030, Edirne, Turkey.
    • Natl Med J India. 2020 Jan 1; 33 (1): 22-23.

    AbstractInvasive fungal infections are a major cause for morbidity and mortality in patients with acute myeloid leukaemia (AML). Long duration of hospitalization and increased costs are secondary burdens for patients and caregivers. The clinical manifestations are variable with a spectrum of different organs or systems. Factors related with invasive fungal infections may be categorized as host-related including the underlying disease, treatment and colonization status and pathogen-related including the capacity of the microorganism for defence, growth, tolerance and tissue affinity. The diagnosis of invasive fungal infection is confirmed with histopathological or microbiological demonstration of the microorganism, and commonly treatments are based on probability rather than definitive diagnosis due to patients fragile conditions preventing interventions. We aimed to present the less frequent yet difficult-to-treat organism, Verticillium causing invasive fungal infection in a patient with AML undergoing remission induction therapy.

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