• Shuai Han, Ting Wang, Dongjie Jiang, Yang Yu, Yu Wang, Wangjun Yan, Wei Xu, Ming Cheng, Wang Zhou, and Jianru Xiao.
• Department of Bone Tumor Surgery, Spine Tumor Center, Changzheng Hospital, Second Military Medical University, Fengyang Rd 415#, Huangpu District, Shanghai, China.
• Eur Spine J. 2015 Aug 1; 24 (8): 1786-91.

PurposeThe aim of this study was to provide some useful insights into the clinical and imaging presentations, treatment and prognostic factors in patients with neurological deficit caused by clear cell renal cell carcinoma (CCRCC) spinal metastases for the sake of designing individualized therapeutic plans for such patients.MethodsA total of 30 patients with neurological deficit due to CCRCC spinal metastases who received surgery in our department were identified during an 8-year period from 2003 to 2012 and used for discussion of treatment options for CCRCC spinal metastases on the basis of literature review and our own experience.ResultsUnivariate analysis showed that age (≤45 years/>45 years), visceral metastasis, Tomita score (3-5/6-8), Tokuhashi score (4-9/10-12) and radiotherapy were suggested as the potential prognostic factors. However, the multivariate Cox regression model showed that only Tokuhashi score was an independent prognostic factor.ConclusionsTokuhashi score 10 or more is a favorable prognostic factor of CCRCC spinal metastasis.

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