• Crit Care · Feb 2021

    Review

    SARS-CoV-2 pneumonia-receptor binding and lung immunopathology: a narrative review.

    • Maria Clara Saad Menezes, Diego Vinicius Santinelli Pestana, Gustavo Rosa Gameiro, da Silva Luiz Fernando Ferraz LFF Department of Pathology, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil., Ėlodie Baron, Jean-Jacques Rouby, and Auler José Otavio Costa JOC Jr 0000-0002-3919-1743 Anesthesiology and Intensive Care Department, Instituto Do Coração (InCor), Hos.
    • Anesthesiology and Intensive Care Department, Instituto Do Coração (InCor), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Av Dr Arnaldo, Número 455, São Paulo, SP, 01246903, Brazil.
    • Crit Care. 2021 Feb 8; 25 (1): 53.

    AbstractThe current pandemic of COVID-19 caused thousands of deaths and healthcare professionals struggle to properly manage infected patients. This review summarizes information about SARS-CoV-2 receptor binding dynamics and intricacies, lung autopsy findings, immune response patterns, evidence-based explanations for the immune response, and COVID-19-associated hypercoagulability.

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