• Amey R Savardekar, Sachin Goudihalli, Debajyoti Chatterjee, Chirag K Ahuja, and Pravin Salunke.
• From the Departments of *Neurosurgery †Pathology, and ‡Radiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
• Spine. 2014 Nov 15;39(24):E1488-92.

Study DesignCase report and review of the relevant literature.ObjectiveTo present a case of primary spinal myoepithelioma and discuss its clinical, radiological and histopathological characteristics. We report a long-term follow-up of 5 years.Summary Of Background DataMyoepithelial neoplasms, represent a diverse morphological and biological spectrum of tumors, composed of epithelial and myoepithelial elements. Primary myoepithelioma of the bone is extremely rare and very few cases of spinal myoepitheliomas have been reported till date.MethodsA 50-year male, presenting with complaints of paraparesis and difficulty in walking, was diagnosed to have an expansile lytic lesion involving the D10 vertebral body with paraspinal extension. The patient underwent D10 laminectomy and gross total resection of the tumor. Patient's power improved postoperatively, and he returned to his full functional status.ResultsLong-term follow-up of 5 years reveals 2 recurrences, despite gross total resection at the initial surgery followed by radiotherapy. Histopathology, at the third surgery, documents the transformation of myoepithelioma into myoepithelial carcinoma.ConclusionPrimary myoepithelioma of spine is very rare. Gross total resection with wide resection margins in the paraspinal region should be used to tackle this rare entity as the role of adjuvant therapy is doubtful. Long-term follow-up is a must.

19 keywords...

hide…