• A&A practice · Feb 2021

    Case Reports

    Intraoperative Use of Angiotensin II for Severe Vasodilatory Shock During Liver Transplantation: A Case Report.

    • Kati Running, Devin Weinberg, William Trudo, Cinnamon L Sullivan, and Gaurav P Patel.
    • From the Department of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia.
    • A A Pract. 2021 Feb 11; 15 (2): e01402.

    AbstractRefractory hypotension is a known entity in liver transplantation. Catecholamine and vasopressin infusions are first-line therapies. There has been recent interest in angiotensin II (Ang-2) as an alternative vasopressor; however, liver failure patients were excluded from the original trials. Ang-2 has potential in this patient population. This case discusses a patient who received an infusion of Ang-2 during a liver transplant for combined liver failure-induced distributive shock and septic shock. It is the first known successful use of intraoperative Ang-2 in this situation, and it shows that Ang-2 may be safe in liver transplantation when traditional therapies fail.Copyright © 2021 International Anesthesia Research Society.

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