• Med. Clin. North Am. · Mar 2021

    Review

    Vaccinations in Patients with Rheumatic Disease: Consider Disease and Therapy.

    • Cassandra Calabrese.
    • Department of Rheumatologic & Immunologic Disease, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A50, Cleveland, OH 44195, USA. Electronic address: calabrc@ccf.org.
    • Med. Clin. North Am. 2021 Mar 1; 105 (2): 213-225.

    AbstractPatients with rheumatic diseases are susceptible to infections due to their underlying disease states as well as from immunosuppressive medications, highlighting the importance of vaccination, these same factors also pose challenges to vaccine efficacy, safety, and uptake. This article reviews the impact of immunosuppressive therapies and rheumatic disease on vaccine efficacy in this vulnerable patient population as well as discusses best practices.Copyright © 2020 Elsevier Inc. All rights reserved.

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