• Med. Clin. North Am. · Mar 2021

    Review

    Management and Cure of Gouty Arthritis.

    • Sarah F Keller and Brian F Mandell.
    • Department of Rheumatic and Immunologic Diseases, The Cleveland Clinic, 9500 Euclid Avenue A50, Cleveland, OH 44915, USA. Electronic address: kellers@ccf.org.
    • Med. Clin. North Am. 2021 Mar 1; 105 (2): 297-310.

    AbstractGout is the most common inflammatory arthritis in the United States. Gouty arthritis is associated with significant morbidity and mortality and is caused by hyperuricemia. Gout is effectively managed and potentially cured by decreasing the overall urate burden with serum urate-lowering therapy. When serum urate is maintained at less than 6.0 mg/dL urate deposition is resolved and gout can be cured. Unfortunately, owing to a lack of physician monitoring and dose escalation the majority of patients do not achieve these urate levels.Copyright © 2021 Elsevier Inc. All rights reserved.

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