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Internal medicine journal · Jan 2021
Faecal microbiota transplantation for recurrent Clostridioides difficile infection: an Australian experience - effective, safe, yet room for improvement.
- Ayushi Chauhan, Ross Apostolov, Daniel van Langenberg, and Mayur Garg.
- Department of Gastroenterology, Eastern Health, Melbourne, Victoria, Australia.
- Intern Med J. 2021 Jan 1; 51 (1): 106-110.
AbstractFaecal microbiota transplantation (FMT) is reportedly effective and safe for the management of recurrent or refractory Clostridioides difficile infection (CDI), yet real-world data of outcomes of FMT in Australia are limited. In this series, FMT safely resulted in resolution of CDI in 19 patients with reduced healthcare utilisation after 25 FMT, but one patient was diagnosed with an anti-nuclear antibody-positive constitutional illness and Hashimoto thyroiditis following FMT. Further prospective evaluation of the utility of FMT earlier in CDI treatment algorithms to minimise cost and morbidity, and recipient follow up for immune-mediated conditions, is required.© 2021 Royal Australasian College of Physicians.
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