• Der Internist · Jul 2021

    Case Reports

    [Treatment-refractory anaemia in a 35-year-old heart transplant recipient on chronic hemodialysis].

    • Christoph Schröder, Johannes Roeles, Adrian Schwarzer, Michael Heuser, Jennifer Retzlaff, and Marcus Hiß.
    • Klinik für Nieren- und Hochdruckerkrankungen, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, 30625, Hannover, Deutschland. schroeder.christoph.nph@mh-hannover.de.
    • Internist (Berl). 2021 Jul 1; 62 (7): 768-771.

    AbstractThis article presents a case of pure red cell aplasia in a 35-year-old heart transplant recipient on chronic hemodialysis. Elevated parvovirus B19 immunoglobulin M blood levels were detected along with a high viral load of 80 billion IU/ml quantified by polymerase chain reaction. Bone marrow examination revealed giant proerythroblasts confirming parvovirus B19 infection. High-dose intravenous immunoglobulin was used for treatment. Anaemia had significantly improved 4 weeks later. Parvovirus B19 infection should be excluded in organ transplant recipients with anaemia due to ineffective erythropoiesis.

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