• Luca Miceli, Rym Bednarova, Iliana Bednarova, Alessandro Rizzardo, Lorenzo Cobianchi, Francesca Dal Mas, Helena Biancuzzi, Tiziana Bove, Fabrizio Dal Moro, and Fabio Zattoni.
• Luca, MD, Miceli is with the Department of Pain Medicine, IRCCS CRO di Aviano, Aviano, Italy. Rym Bednarova, MD, is with the Department of Anaesthesia, Intensive Care and Pain Medicine, Hospital of Latisana, Latisana, Italy. Iliana Bednarova, MD, is with the Department of Radiology, ASUGI, Hospital of Gorizia-Monfalcone, Gorizia, Italy. Alessandro Rizzardo, MD, is with the Intensive Care Unit, Papa Giovanni XXIII Hospital, Monastier, Italy. Lorenzo Cobianchi, MD, PhD (Prof.), is with the Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy and Department of General Surgery, Foundation IRCCS San Matteo Hospital, Pavia, Italy. Francesca Dal Mas, MSc, JD, PhD, is with the Department of Management, Lincoln International Business School, University of Lincoln, Lincoln, UK and Ipazia, International Observatory on Gender Research, Rome, Italy. Helena Biancuzzi, JD, is with the Ipazia, International Observatory on Gender Research, Rome, Italy. Tiziana Bove, MD (Prof.), is with the Department of Anaesthesia, Intensive Care and Pain Medicine, University of Udine, Udine, Italy. Fabrizio Dal Moro, MD (Prof.), is with the Urology Unit, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy. Fabio Zattoni, MD, PhD, F.E.B.U., is with the Urology Unit, Department of Medicine, Udine University Hospital, Udine, Italy.
• J Pain Palliat Care Pharmacother. 2021 Mar 1; 35 (1): 23-30.

AbstractItaly adopted a law on chronic pain in March 2010, which focused on detection and management of this symptom, that affects approximately 25% of the population. The aim of this study is to analyze the interest of the Italian population in palliative care and chronic pain and to understand whether the Law 38/2010 made an impact on the internet search on chronic pain. Five research parameters were included using Google Trends (chronic pain, anti-inflammatory drugs, opioids, fibromyalgia, medical cannabis) from 2004 to 2019 using "joint point regression analysis." Comparisons of annual relative search volume (ARSV), average annual percentage change (AAPC), and temporal patterns were analyzed to assess loss or gain of interest in research of all the terms after adopting Law 38/2010; collected data were analyzed using Kruskall-Wallis test. The research trend of almost every word increased in time (AAPC > 0) with significant inflexion points after issuing law on chronic pain management in March 2010. Our results suggest the relevance of internet search engines, like "Doctor Google," to translate and share knowledge about specific conditions, diseases, and treatment alternatives, with a call to a raise in authoritative scientific voices on the topic, especially when it comes to widespread conditions like chronic pains.

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