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- Kirsti A Campbell, Hirsh D Trivedi, and Sanjiv Chopra.
- Beth Israel Deaconess Medical Center, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address: kacampbe@bidmc.harvard.edu.
- Am. J. Med. 2021 Jun 1; 134 (6): 727-734.
AbstractCirrhosis contributes significantly to morbidity and mortality worldwide. Infections in patients with cirrhosis are common and significantly impact health-related quality of life. As our understanding of immune dysfunction associated with cirrhosis grows and as rates of drug-resistant organisms increase, the management of infections in cirrhosis has become increasingly nuanced. In this review, we discuss the current understanding of cirrhosis-associated immune deficiency, review the most common infections in patients with cirrhosis, and highlight techniques for the general clinician in the prevention and treatment of infections in this high-risk population.Copyright © 2021 Elsevier Inc. All rights reserved.
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