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- Jessica Siak, Nir Flint, Hezzy G Shmueli, Robert J Siegel, and Florian Rader.
- Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, Calif.
- Am. J. Med. 2021 Jun 1; 134 (6): 735-744.e1.
AbstractThe medicinal properties of colchicine have been recognized for centuries. Although previously used for gout and familial Mediterranean fever, its immune-modulating, anti-inflammatory, and antifibrotic effects are increasingly recognized as beneficial in the treatment of cardiovascular disorders. In this systematic review, we summarize the current evidence on colchicine's effectiveness in 1) pericarditis, 2) coronary artery disease, and 3) atrial fibrillation. We also discuss the safety, potential adverse effects, and common drug interactions that should be considered during use.Copyright © 2021 Elsevier Inc. All rights reserved.
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