• Int J Med Sci · Jan 2021

    Review

    PM2.5-related cell death patterns.

    • Yunxia Wang, Yijue Zhong, Jiping Liao, and Guangfa Wang.
    • Department of Respiratory and Critical Care Medicine, Peking University First Hospital, Beijing, China.
    • Int J Med Sci. 2021 Jan 1; 18 (4): 1024-1029.

    AbstractWith the increasingly serious problem of environmental pollution, the health problems caused by PM2.5 are gradually coming into our line of sight. Previous researches have indicated that air pollution is nearly related to various diseases, but few studies have focused on the exact function mediated by particulate matter less than 2.5 (PM2.5) in these diseases. PM2.5 is known to induce multiple ways of cell death, including autophagy, necrosis, apoptosis, pyroptosis and ferroptosis. Therefore, it is of much importance to understand the different ways of cell death caused by PM2.5 in the pathogenesis and treatment of PM2.5-related diseases. This present review is an insight of multiple ways of PM2.5‑induced cell death in different diseases.© The author(s).

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