• Pu Yang, Xia Wang, Pin Liu, Cong Wei, Bingyan He, Junwen Zheng, and Dongchi Zhao.
• Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan University Children's Digital Health and Data Center, Wuhan, China.
• J. Clin. Virol. 2020 Jun 1; 127: 104356.

BackgroundSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is causing an outbreak of pneumonia in Wuhan, Hubei Province, China, and other international areas.ObjectiveHere, we report the clinical characteristics of the newborns delivered by SARS-CoV-2 infected pregnant women.MethodsWe prospectively collected and analyzed the clinical features, laboratory data and outcomes of 7 newborns delivered by SARS-CoV-2 infected pregnant women in Zhongnan Hospital of Wuhan University during January 20 to January 29, 2020.Results4 of the 7 newborns were late preterm with gestational age between 36 weeks and 37 weeks, and the other 3 were full-term infants. The average birth weight was 2096 ± 660 g. All newborns were born without asphyxia. 2 premature infants performed mild grunting after birth, but relieved rapidly with non-invasive continuous positive airway pressure (nCPAP) ventilation. 3 cases had chest X-ray, 1 was normal and 2 who were supported by nCPAP presented mild neonatal respiratory distress syndrome (NRDS). Samples of pharyngeal swab in 6 cases, amniotic fluid and umbilical cord blood in 4 cases were tested by qRT-PCR, and there was no positive result of SARS-CoV-2 nucleic acid in all cases.ConclusionsThe current data show that the infection of SARS-CoV-2 in late pregnant women does not cause adverse outcomes in their newborns, however, it is necessary to separate newborns from mothers immediately to avoid the potential threats.Copyright © 2020 Elsevier B.V. All rights reserved.

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