• Menopause · Mar 2016

    Bone structure and turnover in postmenopausal women with type 2 diabetes mellitus.

    • Farideh Razi, Mahnaz Esmaili, Ensieh Nasli Esfahani, Parichehreh Yaghmaei, Mostafa Qorbani, Zahra Mohammadi, Abbasali Keshtkar, Patricia Khashayar, and Bagher Larijani.
    • 1Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran 2Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran 3Department of Community Medicine, Alborz University of Medical Sciences, Karaj, Iran 4Department of Epidemiology and Biostatistics, Iran University of Medical Sciences, Tehran, Iran 5Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran 6Department of Health Sciences Education Development, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 7Center for Microsystems Technology, Imec and Ghent University, Gent-Zwijnaarde, Belgium 8Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
    • Menopause. 2016 Mar 1; 23 (3): 280-5.

    ObjectiveConsidering the high prevalence of diabetes and osteoporosis in Iranians, the current research was conducted to study the correlation between these two diseases in a group of postmenopausal women.MethodsThe present study was conducted on postmenopausal women recruited in the third phase of the Iranian Multi-centric Osteoporosis Study. They were divided into two groups (diabetic and nondiabetic) based on their diabetes history and laboratory results. The serum levels of bone markers and bone mineral density values were compared between the two groups.ResultsA total of 110 postmenopausal women were included. Although bone mineral density values were nonsignificantly higher in diabetic postmenopausal women, there was no considerable difference between the prevalence of osteoporosis or serum levels of bone markers in the two groups.ConclusionsThere is no difference in bone mass values or bone turnover process between Iranian postmenopausal women with or without diabetes.

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