• Anthony Iacco, Adewunmi Adeyemo, Thomas Riggs, and Randy Janczyk.
• Department of Surgery, William Beaumont Hospital System, Oakland University, Royal Oak, MI, USA. Electronic address: anthony.iacco@beaumont.edu.
• Am. J. Surg. 2014 Sep 1; 208 (3): 480-4; discussion 483-4.

BackgroundComplex ventral hernias remain a challenge. We present a study evaluating outcomes of complex ventral hernia repair using human-derived acellular dermal matrix (AlloDerm) and porcine-derived acellular dermal sheet (Permacol).MethodsA retrospective review of 251 patients undergoing complex hernia repair was performed. Primary outcome was hernia recurrence; and secondary outcomes included early and late complications and mortality.ResultsRecurrence for Permacol versus AlloDerm was 32% versus 47% (P = .02). There was a difference in early complications (48% vs 30%, P = .007) and also late complications (30% vs 21%, P = .16) of Permacol versus AlloDerm. Overall survival was 85% for the Permacol group versus 78% for the AlloDerm group (P = .23). Recurrence for Permacol versus AlloDerm for underlay technique was 19% versus 22% and that for bridging technique was 44% versus 57%.ConclusionThere exists a high complication rate from both Permacol and AlloDerm in complex ventral hernia repair especially when used as a fascial bridge.Copyright © 2014 Elsevier Inc. All rights reserved.

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