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Mult Scler Relat Disord · Nov 2020
Letter Case ReportsBenign SARS-CoV-2 infection in MOG-antibodies associated disorder during tocilizumab treatment.
- Fabio Giuseppe Masuccio, Marianna Lo Re, Antonio Bertolotto, Marco Capobianco, and Claudio Solaro.
- Department of Rehabilitation, C.R.R.F. "Mons. L. Novarese", Loc. Trompone, Moncrivello, Italy.
- Mult Scler Relat Disord. 2020 Nov 1; 46: 102592.
AbstractMyelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD) represents a demyelinating disorder for which tocilizumab, an anti-IL6 receptor, has been tested to prevent disabling relapses. In a subgroup of patients affected with novel Coronavirus disease (COVID-19), tocilizumab has also increased the survival rate. We present the case of a 31-years-old Caucasian patient who experienced an almost asymptomatic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) infection during treatment with tocilizumab, which was continued due to the very high risk of relapses of the patient. According to this case, tocilizumab might be not discontinued during COVID-19.Copyright © 2020 Elsevier B.V. All rights reserved.
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