• Rev Mal Respir · May 2014

    Case Reports

    [Severe pneumonia due to cytomegalovirus in chronic obstructive pulmonary disease].

    • C Bosc, M Clement, A Deroux, A Mammar, C Pison, and B Camara.
    • Clinique universitaire de pneumologie, hôpital Albert-Michallon, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France. Electronic address: CBosc1@chu-grenoble.fr.
    • Rev Mal Respir. 2014 May 1; 31 (5): 435-8.

    UnlabelledSevere pneumonia due to cytomegalovirus in chronic obstructive pulmonary disease.IntroductionWe describe two cases of immunocompetent patients with chronic obstructive pulmonary disease (COPD) who developed severe cytomegalovirus (CMV) pneumonia. The clinical and radiological context and CMV replication in broncho-alveolar lavage suggested a diagnosis of CMV pneumonia.Case HistoriesWe report two cases in patients with moderate chronic obstructive pulmonary disease not treated with long-term steroid therapy who developed bilateral pneumonia with hypoxaemia. The only pathogen identified was CMV with replication of the virus in the broncho-alveolar lavage. Investigation failed to detect any associated immune deficiency.ConclusionSevere cytomegalovirus pneumonia could be encouraged by the existence of chronic obstructive pulmonary disease due to local inflammatory changes.Copyright © 2013. Published by Elsevier Masson SAS.

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