• Neurosurgery · Feb 2013

    Biography Historical Article

    Everything to gain: Sir Hugh Cairns' treatment of central nervous system infection at Oxford and abroad.

    • Joshua I Chalif, Martin J Gillies, Shailendra A Magdum, Tipu Z Aziz, and Erlick A C Pereira.
    • Nuffield Department of Surgery, John Radcliffe Hospital, Oxford University Hospitals Trust, Oxford, United Kingdom.
    • Neurosurgery. 2013 Feb 1;72(2):135-42; discussion 142.

    AbstractAntibiotics have revolutionized survival from central nervous system (CNS) infections. Sixty years after the death of Sir Hugh Cairns, we present archive material of historical interest from the Radcliffe Infirmary in Oxford from the time of his first trials of penicillin for CNS infection. We discuss Cairns' important wartime and subsequent contributions to antibiosis in CNS infection and include drawings by Audrey Arnott illustrating the surgical techniques used to treat abscesses at the time.

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