• J. Thromb. Haemost. · Feb 2017

    Is stand-alone D-dimer testing safe to rule out acute pulmonary embolism?

    • N van Es, T van der Hulle, H R Büller, F A Klok, M V Huisman, J Galipienzo, and M Di Nisio.
    • Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands.
    • J. Thromb. Haemost. 2017 Feb 1; 15 (2): 323-328.

    AbstractEssentials A stand-alone D-dimer below 750 μg/L has been proposed to rule out acute pulmonary embolism (PE). This was a post-hoc analysis on data from 6 studies comprising 7268 patients with suspected PE. The negative predictive value of a D-dimer <750 μg/L ranged from 79% to 96% in various subgroups. Stand-alone D-dimer testing seems to be unsafe to rule out PE in all patients.© 2016 International Society on Thrombosis and Haemostasis.

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