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- M H Claesson, L P Sorensen, and L Malte.
- Dept. A., University of Copenhagen, Panum Institute, Denmark.
- APMIS. 1988 Jul 1; 96 (7): 618-26.
AbstractMouse spleen cells activated for three days with ConA, but not with PHA and LPS, were found to possess strong veto activity. Thus, ConA-activated spleen cells were capable of preventing a cytotoxic T cell response generated in MLC against the H-2 haplotype of the ConA-activated cells. Radiolabelling and chemical cross-linking of veto-active and veto-inactive cells, followed by immunoprecipitation of H-2, class I antigens, and analyses of the precipitates by one and two dimensional SDS PAGE were performed. By these procedures we were unable to demonstrate qualitative and quantitative differences between precipitates of veto-active and veto-inactive cell populations.
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