• Jia-Yu Shen, Hong-Wei Zhang, Kang-Jun Fan, Huai-Min Liang, Er-Yong Zhang, and Jia Hu.
• Department of Cardiovascular Surgery,West China Hospital,Sichuan University,Chengdu 610041,China.
• Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 May 1; 49 (3): 481-484.

ObjectiveTo evaluate the outcomes of valve replacement of endocarditis using bioprothetic and mechanical valves.MethodsThis study comprised 52 patients [mean age (47±18) yr.,mean follow-up time (6.2±3.8) years] underwent valve endocarditis with bioprotheses,The control group were matched (3∶1) with 156 patients of endocarditis underwent mechanical valves replacement using the following variables: age±5 yr.,body mass index (BMI)±20%,time of operation±1 year,replacement position and sex ratio. And evaluate the effects of using bioprothetic and mechanical valves on perioperative and long-term outcomes of valve replacement of endocarditis.ResultsThe perioperative mortality of the patients receiving bioprothetic and mechanical valves were 17.3%±2.2% and 19.9%±1.8%,respectively,which was independent of valve type (P=0.27). Long-term survival were 56.1%±5.2% and 61.2%±8.1%,respectively (P=0.58). Meanwhile,long-term complication-free survival were 75.0%±3.2% and 82.3%±4.4%,respectively (P=0.29). For the patients younger than or equal to 60 yr.,long-term reoperation rates for bioprothetic and mechanical valves were 41.4%±7.2% and 30.5%±5.4% (P=0.02). For the patients older than 60 yr.,however,reoperation rates were 24.1%±8.5% and 14.7%±5.7% (P=0.36).ConclusionPerioperative mortality and long-term survival are independent to valve types in patients with endocarditis. Mechanical valve shows potential advantage compared with bioprothetic valve in the patients younger than 60-year-old.Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).

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