• Pain · Oct 2011

    Case Reports

    Chronic (neuropathic) corneal pain and blepharospasm: five case reports.

    • David Borsook and Perry Rosenthal.
    • Center for Pain and the Brain, McLean Hospital, Massachusetts General Hospital, and Children's Hospital of Boston, Harvard Medical School, Boston, MA, USA Boston Foundation for Sight, Needham, MA, USA.
    • Pain. 2011 Oct 1; 152 (10): 2427-2431.

    AbstractPain and focal dystonias have been associated with chronic pain conditions such as complex regional pain syndrome. Corneal pain, frequently known as "dry eye", may be a neuropathic pain condition with abnormalities of the nerve plexus. Here we present 5 case histories of patients with defined corneal pain (with associated neuropathic features) and objective measures of changes in the nerve plexus and associated blepharospasm. A putative relationship between pain and blepharospasm suggests potential involvement of the basal ganglia in both these conditions.Copyright © 2011. Published by Elsevier B.V.

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