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Nan Fang Yi Ke Da Xue Xue Bao · Sep 2019
Review[Research progress of the role of postoperative pain in the development of postoperative cognitive dysfunction in geriatric patients].
- Xiaohui Chen, Xiaoqiang Ren, Yabing Ma, Li Ge, Zhongyuan Hu, and Wenjun Yan.
- Department of Anesthesiology, Gansu Provincial People's Hospital, Lanzhou 730000, China.
- Nan Fang Yi Ke Da Xue Xue Bao. 2019 Sep 30; 39 (9): 1122-1126.
AbstractPrevious studies have shown that postoperative cognitive dysfunction (POCD) is related to multiple factors including age, postoperative trauma, inflammation, postoperative pain, and anesthesia, among which postoperative pain is thought to play an important role in the development of POCD. This review summarizes the recent findings in the study of the role of postoperative pain in the pathogenesis of POCD in light of nerve injuries, neural remodeling and stress, and the progress in the prevention and treatment of POCD in elderly patients. It is of vital important to assess the postoperative pain and formulate adequate analgesic regimens for effective prevention and management of POCD to protect the brain functions of elderly patients.
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