• J. Clin. Virol. · May 2011

    Case Reports

    Human rhinovirus C--associated severe pneumonia in a neonate.

    • Eeva Broberg, Jussi Niemelä, Elina Lahti, Timo Hyypiä, Olli Ruuskanen, and Matti Waris.
    • Department of Virology, University of Turku, Kiinamyllynkatu 13, FI-20520 Turku, Finland.
    • J. Clin. Virol. 2011 May 1; 51 (1): 79-82.

    AbstractWe present a case of severe pneumonia, associated with a prolonged infection by a species C rhinovirus (HRV) in a 3-week old neonate. HRV RNA was identified in nasal and nasopharyngeal secretions, bronchoalveolar lavage and bronchial specimens, stool and urine, collected from the patient during a one-month period. No other viral or bacterial agents were detected. Sequence analysis of two regions of the viral genome, amplified directly from the clinical specimens revealed a novel HRV-C variant. These observations highlight the occurrence of severe neonatal infections caused by HRVs and the need of rapid viral diagnostics for their detection.Copyright © 2011 Elsevier B.V. All rights reserved.

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