• Ci He, Zhi-gang Yang, Zhi-gang Chu, Zhi-hui Dong, Yun-ming Li, Heng Shao, and Wen Deng.
• Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
• Eur J Radiol. 2011 Dec 1; 80 (3): e361-5.

PurposeTo clarify the differences of the carotid and cerebrovascular disease between patients with and without type 2 diabetes using dual-source CT angiography.Materials And MethodsDual-source CT angiography of the carotid and cerebrovascular arteries was performed in 79 type 2 diabetic patients and 207 non-diabetic patients. The type, extent and distribution of plaques, and luminal stenosis were compared.ResultsCompared with non-diabetic patients, diabetic patients had a higher overall incidence of plaque (p<0.05) and cerebral infarction (p<0.05). Among these plaques, no differences were observed in the subtype of plaques between these two cohorts (all p>0.05), as well as for the number of diseased segments and the distribution of plaques; both mainly involved the bilateral cavernous segment of the internal carotid artery. As for the stenosis, non-obstructive lesions were more common in diabetic patients (p<0.05). There was no difference in the segment number of stenosis (≥30% and ≥70%) between these two groups (all p>0.05).ConclusionDiabetes is associated with a higher incidence of plaque and non-obstructive stenosis. However, no significant differences were observed in the type, extent and distribution of involved plaques between diabetic and non-diabetic patients.Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

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