• Chao Zhan, Zhao-Duan Hu, Yan Zhao, Xiao-Ming Fang, Wei Cheng, Song Lu, and Zhi-Wei Chen.
• Hubei University of Chinese Medicine, Wuhan.
• Medicine (Baltimore). 2021 Mar 5; 100 (9): e25039e25039.

ObjectiveTo compare and evaluate the clinical effects on patients with poststroke insomnia of various acupuncture and acupuncture-related therapies.MethodsIn order to analyze the direct and indirect evidence from related studies, we used network meta-analysis (NMA). In order to collect randomized controlled trials (RCTs) of acupuncture and related therapies in the treatment of poststroke insomnia, 3 English and 4 Chinese databases were searched. After 2 researchers independently screened the literature, extracted the information, and assessed the probability of bias in the included studies, the data was analyzed using Stata15.0 and WinBUGS1.4.3 software.ResultsBased on the existing data, the pros and cons of different acupuncture-related therapies are compared extensively, the effectiveness of different acupuncture-related therapies is ranked compared to drugs with hypnotic effect in poststroke insomnia care, and the best methods or combinations of acupuncture intervention are summarized.ConclusionThis study will provide new evidence for the safety and effectiveness of acupuncture-related therapies in the treatment of poststroke insomnia, and may be helpful for clinicians, poststroke insomnia patients, and clinical guideline makers to choose the optimal combination of acupuncture for the treatment of poststroke insomnia.Registration NumberINPLASY202120028.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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