• Iris Udasin, Clyde Schechter, Laura Crowley, Anays Sotolongo, Michael Gochfeld, Benjamin Luft, Jacqueline Moline, Denise Harrison, and Paul Enright.
• University of Medicine and Dentistry of New Jersey,- Robert Wood Johnson Medical School, Piscataway, New Jersey, USA. udasin@eohsi.rutgers.edu
• J. Occup. Environ. Med. 2011 Jan 1; 53 (1): 49-54.

ObjectiveDetermine if World Trade Center (WTC) disaster responders had lower lung function and higher bronchodilator responsiveness than those with respiratory symptoms and conditions.MethodsWe evaluated cardinal respiratory symptoms (dyspnea, wheezing, dry cough, productive cough) and determined the difference in FEV1, FVC, and bronchodilator responsiveness.ResultsAll respiratory symptoms were associated with a lower FEV1 and FVC, and a larger bronchodilator response. Responders reporting chronic productive cough, starting during WTC work and persisting, had a mean FEV1 109 mL lower than those without chronic persistent cough; their odds of having abnormally low FEV1 was 1.40 times higher; and they were 1.65 times as likely to demonstrate bronchodilator responsiveness.ConclusionsResponders reporting chronic persistent cough, wheezing or dyspnea at first medical examination were more likely to have lower lung function and bronchodilator responsiveness.

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