• Sabuj Kanti Mistry, Elizabeth Harris, and Mark Harris.
• Centre for Primary Health Care and Equity, University of New South Wales, Sydney, Australia. smitra411@gmail.com.
• J Gen Intern Med. 2021 Sep 1; 36 (9): 275527712755-2771.

BackgroundThis review was carried out to synthesize the evidence of the effectiveness of community health worker (CHW) navigation in primary care chronic disease management.MethodsWe searched the English language literature between January 1990 and March 2020 in Medline, Embase, Emcare, PubMed, Psych Info, CINAHL, Scopus, and Medline Epub ahead of print. Data extraction, quality rating, and assessment of the reporting of interventions were performed by two reviewers independently and the findings were synthesized narratively.ResultsTwenty-nine articles met the inclusion criteria. All but two were carried out in the USA and half were randomized controlled trials. Six of the 29 studies were of strong methodological quality while 12 were moderate and 11 weak. Overall, CHW navigation interventions were effective in increasing adherence to cancer screening and improving use of primary care for chronic disease management. There was insufficient evidence that they improved clinical outcomes or risk factors and reduced use of secondary or tertiary care or that they were cost-effective. However, criteria for recruitment, duration, and mode of training and supervision arrangements varied greatly between studies.DiscussionCHW navigation interventions improved aspects of chronic disease management. However, there is insufficient evidence of the impact on patient experience, clinical outcomes, or cost-effectiveness of the interventions. Future research should focus on standardizing organizational components of the CHW navigation interventions and evaluating their cost-effectiveness.Protocol RegistrationThe review protocol was published in PROSPERO (CRD42020153921).© 2021. Society of General Internal Medicine.

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