• Public health · Apr 2018

    The correlation between National Health Service trusts' clinical trial activity and both mortality rates and care quality commission ratings: a retrospective cross-sectional study.

    • L Jonker and S J Fisher.
    • Cumbria Partnership NHS Foundation Trust, Research & Development Department, Carlisle, CA1 3SX, UK; University of Cumbria, Carlisle, CA1 2HH, UK. Electronic address: leon.jonker@cumbria.nhs.uk.
    • Public Health. 2018 Apr 1; 157: 1-6.

    ObjectivesEvidence supporting the notion that clinical research activity in itself is of benefit to organisations as a whole is inconclusive. In the recent past, a positive association between research activity and reduced mortality has been shown. This study aimed to ascertain if clinical research activity is associated with established organisational outcome measures.Study DesignRetrospective cross-sectional study.MethodsFor 129 English National Health Service hospital Trusts, National Institute for Health Research study activity data, Summary Hospital-level Mortality Indicator (SHMI) scores and Care Quality Commission (CQC) ratings were collected. Research activity was controlled for Trust size by dividing it by clinical staffing levels. Multiple linear regression and Spearman correlation analyses were performed.ResultsAlthough there is a significant association between the number of studies and participants with both SHMI score and CQC rating, one particular variable is correlated more significantly than others: the number of participants recruited into interventional studies. It shows a significant correlation with better CQC ratings (standardised coefficient beta 0.26, P-value 0.003) and lower SHMI scores (standardised coefficient beta -0.50, P-value 0.001).ConclusionsThe mortality-related results corroborate with other published data showing a correlation between increased research and reduced deaths. Furthermore, there is also a statistically significant association between clinical trials activity and improved CQC ratings. However, these tie-ins are predominantly driven by the number of participants in interventional research rather than observational research activity.Copyright © 2018 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

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